ART PRP
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What is the ART PRP?
The ART PRP features:
Functionally closed system to minimize sterile breaks
Thumbwheel allows for selective deconstruction of fluid stack for personalized fluid products
Efficient concentration yields ultra-low hematocrit with only 1 spin
15-20 minute processing time
Adjustable white blood cell concentration for leukocyte-depleted product
Consistently achieves high yields of platelets and mononuclear cells
GFC = Growth Factor Concentrate = Concentrated Plasma
GFC Clot = Fibrin Glue with Proteins & Growth Factors!
Includes:
- (1) ART PRP Disposable
- (1) ACD-A
- (1) 35mL Syringe
- (1) 60mL Syringe
- (1) 19G Butterfly needle
- (1) 18G Blunt fill needle
- (3) Alcohol pads
- (1) Tourniquet
- (1) Adhesive bandage
- (2) F-F luer connectors
Features
- Fully integrated device to minimize sterile breaks
- Disposable
- Thumbwheel allows for variable processing volume
- Only BMC device on the market with integrated fibers
Benefits
- High progenitor cell recovery (avg 90 %)1
- High platelet recovery (avg 71 %)1
- Eliminates turbulence by keeping buffy coat in the collection zone
- Ultrafiltration of plasma to obtain essential proteins & growth factors (3x total protein concentration)2
What Proteins, Growth Factors, and Molecules are Present in GFC?2
- VEGF5
- New blood vessel growth
- Endothelial cell migration and proliferation
- PDGF5
- New blood vessel growth
- MSC recruitment and proliferation
- Helps form bone
- Increases collagen synthesis
- TGF-Beta5
- MSC proliferation
- Bone matrix deposition
- FGF5
- MSC proliferation
- Wound healing
- Alpha 2-Macroglobulin (A2M)6
- Prevents cartilage degeneration
- IRAP3
- Interleukin-1 receptor antagonist protein
- High levels in bone marrow
- Decreases inflammation
- FIBRINOGEN5
- Critcal for clot formation
| Cell Type | Platelets |
| Cell Source | Whole Blood |
| Cell Content / Recovery | 71% platelet recovery1 |
| Protein Concentrate | Yes |
| FDA Status | Class II |
1 Karli et al. Autologous Regenerative Therapies: Rapid Concentration of Progenitor Cells, Platelets, and Proteins at the Point-of-Care” TERMIS Annual Meeting. (2015) Boston, MA
2 Monteforte et al. “Autologous Protein Scaffold Isolated from Platelet Poor Plasma in Bone Marrow Concentrate” World Stem Cell Summit. (2016) West Palm Beach, FL.
3 Cassano, Jennifer M., et al. “Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration.” Knee Surgery, Sports Traumatology, Arthroscopy (2016): 1-10.
4 Monteforte et al. “Autologous Protein Scaffold Isolated from Platelet Poor Plasma in Bone Marrow Concentrate” World Stem Cell Summit. (2016) West Palm Beach, FL.
5 Barrientos, Stephan, et al. “Growth factors and cytokines in wound healing.” Wound Repair and Regeneration 16.5 (2008): 585-601.
6 Wang, Shaowei, et al. “Identification of α2‐Macroglobulin as a Master Inhibitor of Cartilage‐Degrading Factors That Attenuates the Progression of Posttraumatic Osteoarthritis.” Arthritis & rheumatology 66.7 (2014): 1843-1853
Additional information
| revision | F |
|---|---|
| gtin-14 | 00817771027545 |
| case-quantity | 6 |
Related Products
ART PRP Plus
(SKU: 0885-2000)
The ART PRP PLUS system processes autologous whole blood at the point of care. The system recovers a high percentage of platelets and growth factors by allowing a selection of concentrate from a patented controlled collection system in the centrifuged stack. The integrated filter allows for the ultrafiltration of proteins from the platelet poor plasma.
More detail
ART Two Step (pending FDA approval)
(SKU: 1651-0001)
The ART PRP Two Step is anticipated for released in August of 2018.
More detail
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