ART PRP
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What is the ART PRP?
The ART PRP features:
Functionally closed system to minimize sterile breaks
Thumbwheel allows for selective deconstruction of fluid stack for personalized fluid products
Efficient concentration yields ultra-low hematocrit with only 1 spin
15-20 minute processing time
Adjustable white blood cell concentration for leukocyte-depleted product
Consistently achieves high yields of platelets and mononuclear cells
GFC = Growth Factor Concentrate = Concentrated Plasma
GFC Clot = Fibrin Glue with Proteins & Growth Factors!
Includes:
- (1) ART PRP Disposable
- (1) ACD-A
- (1) 35mL Syringe
- (1) 60mL Syringe
- (1) 19G Butterfly needle
- (1) 18G Blunt fill needle
- (3) Alcohol pads
- (1) Tourniquet
- (1) Adhesive bandage
- (2) F-F luer connectors
Features
- Fully integrated device to minimize sterile breaks
- Disposable
- Thumbwheel allows for variable processing volume
- Only BMC device on the market with integrated fibers
Benefits
- High progenitor cell recovery (avg 90 %)1
- High platelet recovery (avg 71 %)1
- Eliminates turbulence by keeping buffy coat in the collection zone
- Ultrafiltration of plasma to obtain essential proteins & growth factors (3x total protein concentration)2
What Proteins, Growth Factors, and Molecules are Present in GFC?2
- VEGF5
- New blood vessel growth
- Endothelial cell migration and proliferation
- PDGF5
- New blood vessel growth
- MSC recruitment and proliferation
- Helps form bone
- Increases collagen synthesis
- TGF-Beta5
- MSC proliferation
- Bone matrix deposition
- FGF5
- MSC proliferation
- Wound healing
- Alpha 2-Macroglobulin (A2M)6
- Prevents cartilage degeneration
- IRAP3
- Interleukin-1 receptor antagonist protein
- High levels in bone marrow
- Decreases inflammation
- FIBRINOGEN5
- Critcal for clot formation
| Cell Type | Platelets |
| Cell Source | Whole Blood |
| Cell Content / Recovery | 71% platelet recovery1 |
| Protein Concentrate | Yes |
| FDA Status | Class II |
1 Karli et al. Autologous Regenerative Therapies: Rapid Concentration of Progenitor Cells, Platelets, and Proteins at the Point-of-Care” TERMIS Annual Meeting. (2015) Boston, MA
2 Monteforte et al. “Autologous Protein Scaffold Isolated from Platelet Poor Plasma in Bone Marrow Concentrate” World Stem Cell Summit. (2016) West Palm Beach, FL.
3 Cassano, Jennifer M., et al. “Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration.” Knee Surgery, Sports Traumatology, Arthroscopy (2016): 1-10.
4 Monteforte et al. “Autologous Protein Scaffold Isolated from Platelet Poor Plasma in Bone Marrow Concentrate” World Stem Cell Summit. (2016) West Palm Beach, FL.
5 Barrientos, Stephan, et al. “Growth factors and cytokines in wound healing.” Wound Repair and Regeneration 16.5 (2008): 585-601.
6 Wang, Shaowei, et al. “Identification of α2‐Macroglobulin as a Master Inhibitor of Cartilage‐Degrading Factors That Attenuates the Progression of Posttraumatic Osteoarthritis.” Arthritis & rheumatology 66.7 (2014): 1843-1853
Additional information
| revision | F |
|---|---|
| gtin-14 | 00817771027545 |
| case-quantity | 6 |
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